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Regenerative

PRP Therapy (Vampire Facial)

Platelet growth factors for skin regeneration

Duration
60-90 min (採血含む)
Downtime
1-3 days
Sessions
3-6 sessions (4-6 wk intervals)

About This Treatment

PRP (Platelet-Rich Plasma) therapy concentrates platelets from the patient's own blood via centrifugation. The growth factor-rich plasma is injected or combined with microneedling.

Growth factors (PDGF, TGF-β, VEGF, EGF) activate wound healing cascades, promoting collagen synthesis, angiogenesis, and cell proliferation. Autologous origin means minimal rejection/allergy risk.

Mechanism of Action

Centrifugation (3,500rpm×15min) concentrates platelets 4-8x from whole blood. Activated platelet α-granules release PDGF, TGF-β1/β2, VEGF, EGF, FGF. These stimulate fibroblast collagen synthesis, keratinocyte proliferation, and endothelial cell migration for tissue regeneration.

Indications

General indication (see detailed description)AcneWrinkles / fine linesPoresHair removalSagging / contour

Expected Results

Significant collagen density increase after 3 sessions. 50-70% acne scar improvement after 4-6 sessions. Hair density increase of 20-30% after 3-6 sessions. Results appear at 1-3 months, lasting 6-12 months.

Clinical Evidence

Leo MS, Kumar AS, Kirit R, et al. (2015)
Systematic review of the use of platelet-rich plasma in aesthetic dermatology. J Cosmet Dermatol
Clinical improvement was reported in this study (see original paper for details).
Gentile P, Garcovich S (2020)
Systematic review of platelet-rich plasma use in androgenetic alopecia. Int J Mol Sci
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Injection site swelling/bruising (3-5 days), mild pain. Extremely low infection risk due to autologous origin. Contraindicated with blood disorders or anticoagulant use.

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