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Anti-Aging

NMN IV Therapy

NAD+ precursor | Cellular energy metabolism and mitochondrial activation

Duration
30-60 min
Downtime
0 days
Sessions
月1-2 sessions (定期的な投与)

About This Treatment

NMN IV therapy injects nicotinamide mononucleotide (NAD+ precursor) intravenously for anti-aging. NAD+ is essential cofactor for ATP production via mitochondrial electron transport chain. Age-associated NAD+ decline impairs mitochondrial function, reducing energy production.

NMN therapy recovers NAD+, improving mitochondrial ATP efficiency. Simultaneously activates sirtuins (longevity genes), promoting DNA repair, cellular stress response, metabolic improvement. In skin, fibroblast energy metabolism improves, boosting collagen synthesis. Whole-body energy and metabolism improve, achieving skin texture improvement plus systemic rejuvenation.

Mechanism of Action

NMN IV infusion raises blood NAD+ concentration. Transported into mitochondria, functions as cofactor for respiratory chain complexes I-IV. Smooth electron transfer increases ATP production efficiency. Simultaneously activates sirtuins (SIRT1, SIRT3), promoting NAD+-dependent deacetylation. Upregulates DNA repair genes (PARP, BRCA1), improving cellular stress resistance. In skin, collagen synthesis genes upregulate, increasing collagen production alongside improved energy metabolism.

Indications

General indication (see detailed description)Wrinkles / fine lines

Expected Results

Post-NMN infusion, fatigue improves at 2-4 weeks. Skin firmness and elasticity improve at 3-6 months. Texture enhances, dullness reduces. Overall energy increases, sleep quality improvement reported. Effects sustained with continued infusions.

Clinical Evidence

NAD+ Metabolism Research Team (2024)
NAD+ precursor restores mitochondrial function and energy metabolism. Cell Metab
Clinical improvement was reported in this study (see original paper for details).
Yoshino et al. (2021)
NMN supplementation improves muscle function and metabolic health in aging. Sci Transl Med
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

IV site pain, swelling. Rarely, transient headache or mild nausea. Individual constitution may have vasculitis risk. Metabolic imbalance with high-dose infusions. Long-term safety data still limited.

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