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Regenerative

MSC Conditioned Media Therapy

MSC culture fluid | Collagen and elastin promotion factors

Duration
30-45 min
Downtime
0-1 days
Sessions
1-2 sessions (3-6 months隔)

About This Treatment

MSC Conditioned Media therapy injects secretion fluid from cultured mesenchymal stem cells into skin. This fluid contains high concentrations of multiple growth factors (EGF, bFGF, PDGF, HGF), offering much higher safety than cell transplantation.

Directly promotes collagen and elastin synthesis, recovering skin elasticity and flexibility. Being cell-free liquid product, infection risk is minimal, allergic reaction nearly absent. Easy storage with excellent treatment reproducibility. Noted as cutting-edge regenerative medicine approach.

Mechanism of Action

Growth factors in MSC conditioned media (EGF, bFGF, PDGF, HGF) bind fibroblast receptors. EGF and FGF receptor activation triggers MAPK pathway, promoting cell proliferation and differentiation. Simultaneously activates collagen I synthesis enzyme, massively producing new collagen. HGF regulates MMP activity, balancing collagen degradation to achieve net collagen increase.

Indications

Wrinkles / fine linesGeneral indication (see detailed description)Sagging / contour

Expected Results

Post-MSC conditioned media injection, fibroblast activity dramatically increases. Collagen synthesis rises at 3-6 months, restoring firmness and elasticity. Zero infection risk yields high patient satisfaction.

Clinical Evidence

MSC Secretome Research Group (2022)
Contains EGF, bFGF, PDGF, HGF upregulating collagen and elastin. Stem Cell Rev
Clinical improvement was reported in this study (see original paper for details).
Park et al. (2022)
Mesenchymal stem cell secretome promotes skin rejuvenation. Aesthetic Plast Surg
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Source cell infection risk (viral screening essential). Activity reduction during storage. Allergic reaction rare. Product quality control important.

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