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Morpheus8

Fractional RF microneedling for texture, pores, scars, and laxity

Duration
30-60 min
Downtime
3-7 days
Sessions
1-3 sessions (4-6 wk intervals)

About This Treatment

Morpheus8 is InMode fractional radiofrequency (RF) microneedling. Small electrode pins enter the skin and deliver RF heat around the needle tips, targeting dermal and shallow subdermal coagulation and remodeling.

The standard 24-pin facial tip is described with 0.5-4.0 mm penetration plus an additional thermal profile of about 1 mm, while Body/Deep configurations can reach 7 mm pin depth plus about 1 mm thermal profile. Settings are adjusted by area, skin thickness, and skin type. It is used for texture, pores, acne scarring, and mild to moderate laxity; evidence for pigment disorders such as melasma is more limited.

Mechanism of Action

Morpheus8 delivers 1 MHz RF energy fractionally through 12-, 24-, and 40-pin tips, creating small thermal coagulation zones along the selected needle depth rather than resurfacing the entire epidermal surface. Heat triggers collagen contraction, fibroblast activation, and collagen/elastin remodeling over weeks to months. Deeper settings can affect shallow subdermal fat and septae, so fat loss and nerve-risk management are clinically important.

Indications

Wrinkles / fine linesSagging / contourAcnePoresGeneral indication (see detailed description)

Expected Results

After erythema and edema settle, firmness and texture are typically assessed progressively over 4-12 weeks. Peer-reviewed literature reports use for facial laxity, texture, pores, acne, and scarring, but much of the evidence consists of reviews, case series, and combination protocols, so effect size varies by site, setting, adjunctive treatments, and operator technique.

Energy Settings

Manufacturer
InMode
Country
Israel
Morpheus8 24-pin / Face
Parameters: Pins: 24 insulated, RF: 1MHz, Depth: 0.5-4.0mm + ~1mm thermal profile, Energy level: 5-30 at <=1mm / 5-60 at 2-4mm, Max RF output: 65W
Areas: Full face, jawline, neck, texture, pores, acne scars, mild-to-moderate laxity
Prime 12-pin
Parameters: Pins: 12 semi-insulated, Depth: up to 4.0mm, lower energy commonly used in small or delicate facial subunits
Areas: Periorbital area, upper lip, forehead, small contours
Resurfacing 24-pin
Parameters: Pins: 24 blunt uncoated, Depth: 0.5mm, superficial resurfacing RF
Areas: Superficial texture; caution or avoidance in Fitzpatrick V-VI
Body / Deep 40-pin
Parameters: Pins: 40, Depth: 2-7mm + ~1mm thermal profile, Energy level: 5-60 at 2-7mm
Areas: Body laxity, subdermal adipose remodeling, cellulite protocols

Notes: Settings must be selected by a trained clinician. FDA K200947 states that energy greater than 62 mJ/pin is limited to Skin Types I-IV. For darker skin types, superficial 1mm settings are commonly reduced and resurfacing tips require particular caution.

Source: FDA K200947; InMode Morpheus8 Burst; Hendricks & Farhang 2022

Actual energy, depth, and passes must be selected by a clinician after assessing skin thickness, site, skin type, history, and combination treatments. These are not self-selection settings.

Clinical Evidence

Product-specific / peer-reviewed
Hendricks AJ, Farhang SZ (2022)
Dermatologic facial applications of Morpheus8 fractional radiofrequency microneedling. J Cosmet Dermatol
Clinical improvement was reported in this study (see original paper for details).
Product-specific / peer-reviewed
Dayan E, Chia C, Burns AJ, Theodorou S (2019)
Adjustable Depth Fractional Radiofrequency Combined With Bipolar Radiofrequency: A Minimally Invasive Combination Treatment for Skin Laxity. Aesthet Surg J
Clinical improvement was reported in this study (see original paper for details).
Regulatory / official
U.S. FDA (2020)
510(k) Summary K200947: InMode System with the Morpheus8 Applicators. FDA 510(k) Premarket Notification
Clinical improvement was reported in this study (see original paper for details).
Regulatory / official
U.S. FDA (2025)
Potential Risks with Certain Uses of Radiofrequency (RF) Microneedling. FDA Safety Communication
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Transient erythema, edema, warmth (2-7 days), pinpoint crusting, bruising, pain, hyperpigmentation or hypopigmentation. Deeper or higher-energy settings can cause burns, scarring, fat loss, contour change, numbness, or nerve injury. Careful selection is needed for Fitzpatrick V-VI skin, melasma tendency, thin areas, metal/electronic implants, pregnancy, and active infection or herpes.

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