Juvela (Tocopherol / Vitamin E)
Improves peripheral circulation and provides potent antioxidant protection for enhanced skin turnover and barrier function
About This Treatment
Juvela tablets contain tocopherol acetate (vitamin E), insurance-covered in Japan. As a fat-soluble antioxidant vitamin, it protects cell membrane phospholipids from oxidative stress and improves peripheral circulation to promote skin turnover. Used for pigmentation, chilblains, peripheral circulation disorders, and rough skin.
Mechanism of Action
α-Tocopherol: ①captures peroxyl radicals in lipid bilayer to stop lipid peroxidation chain reactions, ②dilates peripheral vessels improving skin microcirculation, ③modulates prostaglandin metabolism for anti-inflammatory effects, ④forms antioxidant network with vitamin C (which regenerates oxidized vitamin E). Photoprotection and wound healing promotion confirmed.
Indications
Expected Results
Peripheral circulation improvement noticeable at 2-4 weeks. Pigmentation improvement requires 2-3 months. Oral administration increases skin α-tocopherol levels 28-130 fold. Whitening maximized with vitamin C + L-cysteine triple combination.
Clinical Evidence
Risks & Side Effects
Generally safe. High doses (>800IU/day) may increase bleeding risk (interaction with anticoagulants). Rare GI symptoms, headache. Fat-soluble accumulation risk minimal at standard doses. Caution with warfarin.
Interested in this treatment?
Start with an AI skin analysis to check your current skin condition