Cosmetic

Juvéderm Collection

Vycross® technology for graduated hardness and volume restoration | Voluma XC, Vollure XC, Volbella XC, Ultra XC, Volux XC

Duration

15-45 min

Downtime

0-3 days

Sessions

9-24 monthsevery

About This Treatment

Juvéderm (Allergan/AbbVie, USA) is the global market leader in HA fillers. Vycross® technology optimizes 3D cross-linking between HA molecules. Each product has unique hardness (G' value) and particle size for site-specific use.

[Voluma XC] Highest hardness (G'=44kPa), deep injection for cheeks, marionette lines, jawline. [Vollure XC] Medium (G'=21kPa) for nasolabial fold, dynamic lines. [Volbella XC] Softest (G'=9kPa) for lips, tear troughs, periocular zones. [Ultra XC] Intermediate (G'=15kPa) for nasolabial, superficial. [Volux XC] Ultra-firm (G'=48kPa) for skeletal support—nose, jawline, temples.

Mechanism of Action

Vycross® technology uses advanced manufacturing to create more inter-molecular HA cross-links, achieving higher elasticity and durability vs conventional products. Injected gel provides physical volume filling plus biostimulation via HA degradation products, promoting ASC (adipose stem cell) proliferation. Result: sustained volume effect exceeding actual filler volume.

Indications

General indication (see detailed description)Nasolabial / marionette linesLip / mouth contourEye area concernsSagging / contourNose contour

Expected Results

Immediate volume effect. Voluma/Volux lasts 12-24 months, Vollure/Ultra 9-18 months, Volbella 9-12 months. Regular touch-ups maintain rejuvenation.

Clinical Evidence

Sattler G, Casabona G, Nesaratnam N (2019)

A randomized controlled study to evaluate the safety and efficacy of Juvéderm Volux in the treatment of jawline definition. Aesthet Surg J

Clinical improvement was reported in this study (see original paper for details).

Sundaram H, Cassuto D, Picard-Ami LA, et al. (2015)

Improved Results with a Refined Hyaluronic Acid Dermal Filler: A Global Prospective Study. J Cosmet Dermatol

Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Injection swelling/bruising (1-2 weeks). Juvéderm products have excellent safety profile with multiple FDA/EMA approvals. Rare vascular occlusion with tissue necrosis/blindness risk. Emergency hyaluronidase protocol essential. Very rare granuloma formation.

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