Regenerative

Juläine

Swedish next-generation PLLA collagen biostimulator

Duration

30-45 min

Downtime

2-7 days

Sessions

2-3 sessions (4-8 wk intervals)

About This Treatment

Juläine is a PLLA-based collagen biostimulator from Nordberg Medical. It is gaining attention in Europe and the UK as a regenerative injectable focused on natural collagen renewal rather than overfilling.

Mechanism of Action

Uniform PLLA microspheres induce fibroblast response, type I collagen synthesis and ECM remodeling. It changes progressively over weeks to months rather than acting as an immediate HA filler.

Indications

General indication (see detailed description)Wrinkles / fine linesElasticity / firmness

Expected Results

Clinical data report wrinkle severity improvement from 1-2 months in areas such as nasolabial folds. Results are gradual and commonly planned over 2-3 sessions.

Clinical Evidence

Juläine clinical investigators (2025)

Facial rejuvenation with an innovative poly-L-lactic acid biostimulator. J Cosmet Dermatol

Clinical improvement was reported in this study (see original paper for details).

Nordberg Medical (2026)

Juläine of Sweden product and CE information. Manufacturer information

Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Swelling, bruising, tenderness, nodules and overcorrection may occur. Dilution, plane, distribution and standard vascular-safety precautions are important.

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