Cosmetic
Jeuveau / Nuceiva
Aesthetic-focused prabotulinumtoxinA used in the US and Europe
Duration
10-20 min
Downtime
0-1 days
Sessions
3-4 monthsごと
About This Treatment
Jeuveau in the US and Nuceiva in Europe are prabotulinumtoxinA products used for dynamic wrinkles such as glabellar lines. They add another option alongside Botox, Dysport and Xeomin.
Mechanism of Action
Botulinum toxin type A cleaves SNAP-25, reducing acetylcholine release at the neuromuscular junction and weakening dynamic muscle contraction.
Indications
Wrinkles / fine linesGeneral indication (see detailed description)
Expected Results
Phase 3 trials showed efficacy over placebo for glabellar lines. Onset is usually within days and duration is commonly about 3-4 months.
Clinical Evidence
Beer KR, et al. (2019)
Efficacy and safety of prabotulinumtoxinA for glabellar lines. Dermatol Surg / Aesthet Surg J
Clinical improvement was reported in this study (see original paper for details).
U.S. FDA (2019)
Jeuveau prescribing information. FDA Label
Clinical improvement was reported in this study (see original paper for details).
Risks & Side Effects
Bruising, headache, brow ptosis, eyelid ptosis, asymmetry and rare swallowing or breathing symptoms may occur. Off-label areas need clear consent.
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