iS Clinical Active Serum
Sugar-derived molecular complex + plant stem cells next-gen serum
About This Treatment
iS CLINICAL Active Serum is a next-generation serum popular among Hollywood celebrities and professional skincare clinics.
■ Sugar-derived saccharide isomerate: binds to NMF for 72+ hour hydration ■ Arbutin: safe hydroquinone alternative inhibiting tyrosinase ■ Centella asiatica stem cells: collagen I synthesis and anti-inflammation ■ White willow bark: natural salicin for gentle exfoliation
All-in-one serum covering hydration, brightening, exfoliation, and anti-aging.
Mechanism of Action
Saccharide isomerate forms covalent bonds with keratin filaments to physically trap water molecules (deep stratum corneum hydration unlike surface HA). β-arbutin competitively inhibits tyrosinase monophenolase. Centella asiaticoside/madecassoside promote collagen synthesis via TGF-β1 while suppressing NF-κB for anti-inflammatory effects.
Indications
Expected Results
Clinical studies: 31% increase in skin hydration at 4 weeks, 23% improvement in pigmentation score. 8 weeks: reduced pore visibility and overall texture improvement. Anti-inflammatory benefits confirmed for acne-prone skin.
Clinical Evidence
Risks & Side Effects
Low risk. Mild tingling (from willow bark salicin). Arbutin safer than hydroquinone but rare allergic reactions possible. Suitable for all skin types.
Interested in this treatment?
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