Human Placental Extract Therapy
Extracted from human placenta | Contains IGF-1, EGF, FGF, TGF-β1
About This Treatment
Human placental extract therapy injects components extracted from placental tissue from ethically-approved medical facilities. Human placenta contains abundant growth factors (IGF-1, EGF, FGF, TGF-β1) that directly regulate fibroblast gene expression.
Particularly upregulates COL1A1 (collagen I), COL5A3 (collagen V), ELN (elastin), and HAS2 (hyaluronic acid synthase) genes. Results in improved skin structural strength, deep wrinkle reduction, and restored skin volume.
Mechanism of Action
Placental extract factors (IGF-1, EGF, FGF, TGF-β1) bind dermal fibroblast surface receptors. IGF-1 and EGF receptor activation induces nuclear transcription factor NFAT, promoting COL1A1 and COL5A3 transcription. FGF receptor-mediated PI3K/Akt pathway activation simultaneously enhances overall protein synthesis. Structural collagen production increases, dramatically improving skin elasticity.
Indications
Expected Results
A 2022 Scientific Reports paper reports that human placental extract-treated group shows significantly increased skin thickness and collagen density vs control. Average apparent age reduction of 2-3 years noted. Effects persist 3-12 months.
Clinical Evidence
Risks & Side Effects
Ethical concerns. Viral screening (HIV, hepatitis) mandatory. Allergy risk (human-derived). Infection risk minimal but requires proper medical facility administration.
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