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Hair Growth Therapy (HARG/Minoxidil/LED)

Growth factor injection + oral + LED for hair density restoration

Duration
30-60 min (HARG)
Downtime
0 days
Sessions
6 sessions (1x/month)+ oral・topical継続

About This Treatment

HARG therapy injects growth factors (AAPE from adipose stem cells) directly into the scalp. Combined with finasteride/dutasteride oral therapy, topical minoxidil, and low-level laser therapy (LLLT) for comprehensive hair loss treatment.

Addresses both male (AGA) and female pattern hair loss (FPHL) by activating follicular stem cells and inducing anagen.

Mechanism of Action

AAPE growth factors (KGF, PDGF, VEGF, HGF) activate Wnt/β-catenin signaling in follicular stem cells, transitioning telogen follicles to anagen. Finasteride inhibits 5α-reductase type II (reduces DHT). Dutasteride blocks types I and II. Minoxidil causes vasodilation via KATP channels plus direct follicular stimulation. LLLT activates mitochondrial cytochrome C oxidase for increased ATP.

Indications

Hair removalGeneral indication (see detailed description)Elasticity / firmness

Expected Results

HARG: 70-80% of patients show density improvement after 6 sessions (monthly). Finasteride: AGA stabilization + regrowth at 6-12 months. Minoxidil: effects at 4-6 months. LLLT: density increase at 16-26 weeks. Combined program for maximum results.

Clinical Evidence

Fukuoka H, Suga H (2015)
Hair regeneration treatment using adipose-derived stem cell conditioned medium: follow-up with trichograms. Eplasty
Clinical improvement was reported in this study (see original paper for details).
Jimenez JJ, Wikramanayake TC, Bergfeld W, et al. (2014)
Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss. Am J Clin Dermatol
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

HARG: scalp pain/redness (same day). Finasteride: sexual dysfunction (1-2%), contraindicated in women/pregnant. Dutasteride: similar side effects slightly higher. Topical minoxidil: scalp itching/flaking. LLLT: virtually no side effects.

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