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Regenerative

Autologous Fat Grafting

Patient's own fat for natural volume and firmness restoration

Duration
60-90 min
Downtime
7-14 days
Sessions
1 sessions (脂肪生着により永続、追加injectionは1 years後以降)

About This Treatment

Autologous fat grafting harvests patient's own abdominal fat, centrifuges to purify, then injects into facial hollows and wrinkles. Zero allergies (autologous cells). Engrafted fat cells provide long-term volume; adipose-derived stem cells (ADSCs) included enhance skin quality via regenerative factors. Most natural, long-lasting volumization and rejuvenation.

Mechanism of Action

Harvested fat centrifuged and purified to concentrate viable adipocytes for transplant. Injected via fine needle into facial depressions. 30-50% of grafted fat survives via neovascularization, providing permanent volume. ASCs within fat tissue release growth factors (EGF, PDGF, VEGF, HGF) stimulating surrounding tissue and activating fibroblasts for collagen production. Not just volumization but comprehensive skin regeneration.

Indications

Nasolabial / marionette linesGeneral indication (see detailed description)Wrinkles / fine lines

Expected Results

Immediate volume sensation. 3-6 months for fat engraftment, then permanent. 30-40% volume recovery per session. Marked skin quality improvement with enhanced luminosity.

Clinical Evidence

Coleman SR (2006)
Structural fat grafting: more than a permanent filler. Plast Reconstr Surg
Clinical improvement was reported in this study (see original paper for details).
Gir P, Brown SA, Coon D, et al. (2012)
Fat grafting: evidence-based review on autologous fat harvesting, processing, reinjection, and perioperative considerations. Plast Reconstr Surg
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Transient harvest-site swelling/pain (1-2 weeks), injection-site swelling/redness (3-7 days). Rare cyst or fat necrosis. Infection risk: post-op care crucial.

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