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Cosmetic

Evolysse

Next-generation OXIFREE hybrid HA filler technology

Duration
15~25 min
Downtime
24~48 hours
Sessions
初 sessions1 sessions、必要に応じて2 weeks間後に追加

About This Treatment

Evolysse is a next-generation hyaluronic acid filler developed by Across Pharmaceuticals in Switzerland. The proprietary OXIFREE cross-linking technology minimizes oxidative reactions, providing superior stability and longevity. Delivers dynamic facial volumization while maintaining natural facial expressions and movement.

Mechanism of Action

OXIFREE cross-linking technology significantly reduces oxidative degradation inherent in conventional cross-linking methods. The hybrid polymer network maintains elasticity post-injection while providing long-term structural stability and integration with native tissues.

Indications

Wrinkles / fine linesNasolabial / marionette linesGeneral indication (see detailed description)Lip / mouth contour

Expected Results

Immediate volumization upon injection with full integration within 4-6 weeks. Results typically persist for 12-18 months. Maintains natural appearance and facial mobility throughout duration.

Clinical Evidence

Rohrich RJ, Ghavami A, Lemmon JA (2012)
Hyaluronic acid soft-tissue fillers: a systematic review of the literature. Plastic & Reconstructive Surgery
Clinical improvement was reported in this study (see original paper for details).
Micheels P, Vandersmissen B, Bkilder L (2015)
Properties of a new hyaluronic acid filler incorporating a novel cross-linking technology. Journal of Drugs in Dermatology
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Temporary swelling, erythema, and bruising at injection sites are common. Rare allergic reactions and granuloma formation have been documented. Intravascular injection risk is minimal with proper technique.

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