Dental Pulp Stem Cell Therapy
Stem cells from dental pulp | Neurotrophic and growth factors
About This Treatment
DPSC therapy uses stem cells harvested from dental pulp during tooth extraction—enables high self-renewal capacity and secretes multiple bioactive substances. Particularly rich in bFGF, TGF-β, NGF, PDGF, BMPs at high concentrations.
These factors strongly promote fibroblast activation and collagen production. NGF and similar neurotrophic factors also promote nerve regeneration, improving sensory function in age-compromised skin. Uses own tooth, eliminating rejection risk and ethical concerns.
Mechanism of Action
DPSC-secreted factors (bFGF, TGF-β, NGF, PDGF) act on dermal fibroblasts, activating growth factor receptors via Smad and MAPK pathways to promote collagen synthesis. NGF activates TrkA receptors, promoting nerve growth and functional recovery. Also acts as neovascularization promoter, improving skin blood flow.
Indications
Expected Results
Post-DPSC administration, fibroblast activity significantly increases. Collagen synthesis rises at 3-6 months, restoring firmness and elasticity. Sensory skin improvement via neurotrophic factors also reported.
Clinical Evidence
Risks & Side Effects
Extraction risk (tooth loss). Post-extraction pulp chamber infection. Culture contamination risk. Post-injection hypersensitivity rare but standard stem cell therapy risks apply.
Interested in this treatment?
Start with an AI skin analysis to check your current skin condition