Deoxycholic Acid Injection
Injectable deoxycholic acid for submental fat reduction
About This Treatment
Injectable deoxycholic acid disrupts adipocyte membranes and is approved as Kybella/Belkyra for submental fat in several regions. It has stronger regulatory evidence than many generic fat-dissolving cocktails.
It is for pinchable submental fat, not laxity-dominant contour issues.
Mechanism of Action
Deoxycholic acid emulsifies adipocyte membranes; inflammatory clearance by macrophages removes lipid, sometimes with mild fibrosis/tightening.
Indications
Expected Results
Submental volume and contour are assessed after 2-4 sessions. Swelling can be substantial and changes emerge over weeks.
Clinical Evidence
Risks & Side Effects
Swelling, pain, induration, bruising, numbness, marginal mandibular nerve paresis, dysphagia and skin necrosis may occur.
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