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Regenerative

Belotero Revive

HA + glycerol for UV damage repair & skin revitalization

Duration
20-30 min
Downtime
0-1 days
Sessions
2-4 sessions (2-4 wk intervals)

About This Treatment

Belotero Revive by Merz is the world's first HA + glycerol biorevitalization product. Unlike traditional HA skin boosters, it combines glycerol's powerful moisturizing and protective effects, specializing in repairing UV and environmental damage.

Improves skin elasticity, radiance, and hydration simultaneously.

Mechanism of Action

Non-crosslinked HA retains moisture in dermis for immediate hydration. Glycerol strengthens stratum corneum barrier function, reducing TEWL. Synergistic effect stimulates fibroblasts for collagen/elastin synthesis. Antioxidant protection against UV-induced oxidative stress also reported.

Indications

General indication (see detailed description)Wrinkles / fine linesElasticity / firmness

Expected Results

Hydration effect noticeable immediately after first treatment. 2-4 treatment series significantly improves elasticity and radiance. Effects last 6-9 months. Mesotherapy injection technique recommended.

Clinical Evidence

Merz Pharmaceuticals (2024)
Belotero Revive: Clinical evaluation of HA-glycerol combination for skin bio-revitalization. Merz Clinical Data
Clinical improvement was reported in this study (see original paper for details).
Kerscher M, Ogilvie P (2021)
Skinboosters with hyaluronic acid for skin quality improvement. J Drugs Dermatol
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Mild injection pain. Injection site redness/papules (resolve in 12-48 hours). Rare bruising. Slight stinging possible from glycerol content. Allergic reactions (extremely rare).

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