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Regenerative

ADSC Therapy

Stem cells harvested from your own fat | Secretes multiple growth factors

Duration
採取30-60 min+injection30 min
Downtime
3-7 days (採取部位)
Sessions
1 sessions (培養期間2-4 weeks間)

About This Treatment

ADSC therapy harvests fat from abdomen or thigh, isolates and cultures stem cells, then injects into skin. ADSCs secrete EGF, FGF, VEGF, IGF-1, TGF-β1, stimulating fibroblasts.

Promotes collagen I and III synthesis while decreasing MMP-1 and MMP-9 expression to inhibit collagen breakdown. Results in elasticity recovery, wrinkle reduction, and texture improvement. Fat is abundant and easily harvested with zero rejection risk.

Mechanism of Action

ADSC-secreted factors (EGF, FGF, VEGF, IGF-1, TGF-β1) bind fibroblast receptors, activating Ras/MAPK and PI3K/Akt pathways. Fibroblast proliferation and differentiation increase, boosting collagen synthesis. MMP-1 and MMP-9 expression decreases, inhibiting collagen degradation. VEGF promotes neovascularization, improving blood flow and nutrient delivery.

Indications

Wrinkles / fine linesGeneral indication (see detailed description)Sagging / contour

Expected Results

ADSC stem cell activity is high, secreting multiple growth factors from early culture stages. Clinical studies report elasticity improvement, wrinkle reduction, and texture enhancement at 3-6 months. Liposuction procedure is an associated consideration.

Clinical Evidence

Adipose-derived stem cells research group (2020)
Adipose-derived stem cells and their secretory factors as a promising therapy for skin aging. Stem Cell Res Ther
Clinical improvement was reported in this study (see original paper for details).
Zhang et al. (2020)
Application of adipose-derived stem cells in photoaging. Stem Cell Res Ther
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Liposuction surgical risks (swelling, bruising, infection). Rarely, contamination during culture. Post-injection allergic reaction extremely rare (autologous).

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