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Regenerative

AAPE Therapy

Lyophilized proteins from ADSC | Contains ~150 proteins

Duration
採取30 min+injection30-60 min
Downtime
3-7 days (採取部位)
Sessions
複数 sessions (1 sessionsの採取から複数投与可)

About This Treatment

AAPE therapy injects lyophilized powder of secretion products from patient's own adipose stem cells. Contains ~150 proteins and growth factors, excelling at collagen synthesis promotion and skin thickness increase.

Clinical studies report 30% dermal thickness increase with AAPE. Lyophilized product enables long-term storage and easy reconstitution. Requires liposuction but single harvest supplies multiple treatments, economical. Non-cell transplant means high safety, low allergy risk.

Mechanism of Action

~150 AAPE proteins include abundant growth factors (EGF, FGF, VEGF, TGF-β). Bind fibroblast receptors, particularly activating collagen synthesis pathway. Simultaneously decrease MMP expression, inhibiting collagen degradation. Dermal collagen production increases, achieving reported 30% skin thickness increase.

Indications

General indication (see detailed description)Wrinkles / fine linesSagging / contourElasticity / firmness

Expected Results

AAPE increases dermal thickness 30%. Volume sensation recovers at 3-12 months, deep wrinkles significantly reduce. Age-related volume loss reverses. High patient satisfaction.

Clinical Evidence

AAPE Research Group (2018)
Lyophilized ADSC-derived proteins increase dermal thickness by 30%. Stem Cell Res Ther
Clinical improvement was reported in this study (see original paper for details).
Wang et al. (2019)
AAPE promotes fibroblast proliferation and collagen synthesis. J Cosmet Dermatol
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Liposuction surgical risks (swelling, bruising). Potential activity reduction during lyophilization. Infection risk minimal. Allergic reaction rare but theoretical risk exists (protein product).

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