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Regenerative

ULTRACOL PDO Microsphere Filler

Korean PDO microsphere booster for gradual skin-quality, wrinkle, and fold improvement

시술 시간
20-30분
다운타임
1-5일
권장 횟수
2-3회 (4주 간격)

이 치료에 대해

ULTRACOL is a Korean biostimulator that reformulates polydioxanone (PDO), a material widely known from absorbable threads, into injectable microspheres. Rather than acting as an instant volumizer like a classic HA filler, it is positioned more as a skin-quality procedure for rough texture, fine lines, nasolabial-fold skin quality, and early loss of firmness.

In Korea and nearby markets it sits alongside PN, PDLLA, and HA boosters as a newer regenerative category, but product preparation, dilution, injection depth, and particle handling are critical to both outcomes and safety. It is conceptually distinct from thread placement because it relies on microsphere scaffolding and gradual collagen remodeling during PDO hydrolysis.

작용 기전

Uniform PDO microspheres act as a scaffold in the dermis to superficial subcutis, stimulating surrounding fibroblast activity and collagen formation. Because PDO hydrolyzes gradually over time, the treatment is designed for progressive changes in skin density, elasticity, and wrinkle appearance over weeks to months rather than immediate expansion. Poor particle suspension or wrong depth can increase the risk of nodules or irregularity.

적응증

입술·입가주름·잔주름일반 적응증(상세 설명 참고)모공탄력·탄성

기대 효과

A clinical study of ULTRACOL200 reported significant improvement in skin texture and wrinkle volume after two sessions in 31 participants. A comparative ULTRACOL100 study reported reductions in roughness, transepidermal water loss, and pore size with increases in elasticity, hydration, transparency, and density. The expected result is gradual skin-quality improvement over 2-3 sessions rather than dramatic instant contour change.

임상 근거

제품 고유 / 동료심사
Giang NN, Kim HJ, Chien PN, et al. (2024)
An evaluation of the effectiveness of 'ULTRACOL 200' in enhancing nasolabial fold wrinkles through cutaneous repair. Skin Res Technol
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).
제품 고유 / 동료심사
Seoul National University investigators (2024)
An Assessment of the Effectiveness and Safety of ULTRACOL100 as a Device for Restoring Skin in the Nasolabial Fold Region. Cosmetics
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).
간접 근거 / 기기 클래스
Giang NN, Linh LTT, Tien TT, et al. (2025)
Evaluation of Bio-Stimulation Effects of Various Dermal Fillers: Hyaluronic Acid-Based Polynucleotides and Microparticle Fillers in Mouse Model. Aesthetic Plast Surg
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).
간접 근거 / 성분 클래스
Rho NK, Kim HS, Kim SY, et al. (2024)
Injectable "Skin Boosters" in Aging Skin Rejuvenation: A Current Overview. Arch Plast Surg
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).

위험 및 부작용

Swelling, bruising, redness, papules, nodules, textural irregularity, infection, and asymmetry may occur. Unlike HA fillers, reversal is not straightforward, so superficial placement or overcorrection requires careful counseling because of the higher nodule and irregularity risk.

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