SkinCeuticals Phloretin CF
Phloretin 2% + vitamin C 10% + ferulic acid pigment-correcting antioxidant
이 치료에 대해
SkinCeuticals Phloretin CF enhances the antioxidant philosophy of CE Ferulic with pigment-correcting power.
■ Phloretin (2%): apple-derived polyphenol that inhibits GLUT-1 transporter to boost penetration, plus free radical scavenging, cell turnover, and melanin reduction. ■ L-ascorbic acid (10%): collagen synthesis + antioxidant ■ Ferulic acid (0.5%): vitamin C stabilization + synergy
Where CE Ferulic focuses on wrinkles/firmness, Phloretin CF targets pigmentation/tone. Suitable for oily/combination skin.
작용 기전
Phloretin inhibits GLUT-1 transporter to alter stratum corneum permeability, boosting transdermal absorption of subsequent actives. Phloretin also directly scavenges ROS and inhibits tyrosinase monophenolase for melanin suppression. L-ascorbic acid reduces dopaquinone back to DOPA for immediate pigment reduction.
적응증
기대 효과
12-week studies: 20% improvement in skin tone evenness, 27% increased radiance, 16% reduction in discoloration. 24 weeks: 24% fine line reduction. Visible at 4-6 weeks, marked at 12 weeks.
임상 근거
위험 및 부작용
Mild tingling (low pH). Use within 6 months of opening. Brown discoloration indicates oxidation. Less irritating than CE Ferulic.