LINERASE Injectable Type I Collagen
European injectable type I collagen biostimulator for scars, skin density, and regenerative aesthetics
이 치료에 대해
LINERASE is a European injectable heterologous type I collagen product positioned within regenerative aesthetics. It is not primarily a contour-building filler like classic HA gels; instead, it is used as a collagen biostimulator aimed at atrophic acne scars, reduced skin density, fine lines, and lax-quality skin through fibroblast activation and extracellular-matrix remodeling.
Around 2025-2026, international aesthetics has continued shifting toward regenerative injectables beyond simple volumization, including PN, PDRN, PDLLA, PLLA, and collagen-focused approaches. Within that trend, LINERASE stands out because it is positioned as a medical injectable collagen product rather than a topical or supplement-style collagen concept. Because the category is newer and product handling matters, indication selection, source material, preparation, injection plane, and regional regulatory status all need careful verification.
작용 기전
Micronized type I collagen is intended to act as a regenerative scaffold signal in the dermis to superficial soft tissue, promoting fibroblast activation, neocollagenesis, and extracellular-matrix remodeling. The product is not meant to create strong immediate projection; instead, it aims for gradual improvements in texture, density, and elasticity over weeks to months. Because it uses heterologous collagen, patient selection, product handling, and avoidance of superficial uneven deposition remain important.
적응증
기대 효과
In the product-specific prospective study, 30 patients with atrophic acne scars underwent four sessions at 2-week intervals. At 3 months, scar grades improved, physicians rated mean improvement at 6.8/10, patients at 7.2/10, and mean satisfaction at 7.4/10, with improvement sustained to 12 months. Expected changes are gradual rather than dramatic, focusing on scar smoothness, skin density, and overall textural refinement over a series of sessions.
임상 근거
위험 및 부작용
Swelling, redness, bruising, tenderness, papules, nodules, textural irregularity, infection, and asymmetry may occur. Because this is a heterologous collagen product, prior hypersensitivity history and informed consent require extra care. Superficial placement or excessive product can increase palpability and unevenness.