Exosome Therapy (ASCE+)
Human stem cell-derived exosomes for cellular-level regeneration
이 치료에 대해
Exosome therapy utilizes extracellular vesicles (30-150nm) derived from mesenchymal stem cells (MSC) as next-generation regenerative medicine. ASCE+ by ExoCoBio contains growth factors, peptides, mRNA, and lipids.
Through intercellular communication, it promotes collagen remodeling, angiogenesis, and anti-inflammatory effects. Synergistic when combined with microneedling or laser treatments.
작용 기전
Exosomes deliver bioactive cargo (mRNA, miRNA, proteins) to target cells via lipid bilayer. Activates PI3K/Akt/mTOR pathway in fibroblasts for collagen/elastin synthesis. Induces stem cell recruitment via Wnt/β-catenin signaling. Promotes anti-inflammatory cytokines (IL-10, TGF-β1).
적응증
기대 효과
ASCE+ shows early collagen deposition at day 3, dense aligned bundles by day 7, highly organized architecture by day 14. 200-300% enhanced efficacy when combined with microneedling. Effects last 2-3 months; 3-6 sequential treatments recommended.
임상 근거
위험 및 부작용
Transient redness/swelling (24-48 hours). Possible bruising with microneedling. Not FDA-approved (all uses off-label). Quality varies between manufacturers. Allergic reactions (extremely rare).