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Regenerative

Cellderma Skin Plus

Skin foundation reconstruction via human ECM injection

시술 시간
15–30분
다운타임
수일 (경미한 붉음・융기)
권장 횟수
3–5회 (2–3주間間隔)

이 치료에 대해

Cellderma (CellREDM) Skin Plus is a next-generation skin booster based on human acellular dermal matrix (hADM). It directly replenishes ECM components—collagen (Type I & III), elastin, and glycosaminoglycans (GAGs)—as 75µm ultra-fine particles into the dermis, reconstructing the structural foundation lost to aging. Unlike HA fillers, it stimulates fibroblast proliferation and enhances synthesis of collagen, elastin, and angiogenic growth factors (VEGF, FGF, PDGF), improving skin quality at its foundation. hADM is cell-free and MHC-free, minimizing immune rejection risk.

작용 기전

hADM-derived ECM injection into dermis → fibroblast proliferation → enhanced collagen I/III & elastin synthesis → growth factor secretion (VEGF, FGF, PDGF) → reduced TGF-β1 (anti-fibrotic) → neocollagenesis → dermal reconstruction and skin quality improvement

적응증

주름·잔주름일반 적응증(상세 설명 참고)탄력·탄성처짐·윤곽

기대 효과

Most patients notice improved skin density, elasticity, and firmness, reduced pores, and diminished fine lines after 3-5 sessions. In a 20-participant, 20-week RCT, hADM showed statistically significant improvements over HA controls in skin density, elasticity, wrinkle depth, pore area, and hydration.

임상 근거

Kim JH, Park JY, Lee SE, et al. (2025)
Injectable Particulated Human Acellular Dermal Matrix Booster for Skin Restoration: An Integrated Randomized, Split-Face, Double-Blinded Clinical Trial and Preclinical Study. Int J Mol Sci
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).
Hou A, Cohen B, Haimovic A, Elbuluk N. (2024)
Injectable Skin Boosters in Aging Skin Rejuvenation: A Current Overview. Dermatol Surg (PMC Review)
해당 연구에서 임상적 개선이 보고되었습니다(자세한 내용은 원문 논문 참조).

위험 및 부작용

Temporary embossing (small bumps), redness, and injection marks may persist for several days. hADM is cell-free and MHC-free, so immune rejection risk is very low. Shallow injection may cause prolonged bumps; deep injection into fat may reduce efficacy. Nodule formation is rare. Individual results vary; physician consultation required.

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