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Regenerative

Autologous Fibroblast Therapy

Cultured from patient's own fibroblasts | Direct collagen production

Duration
採取15-30 min+injection30-60 min
Downtime
1-2 days
Sessions
1-2 sessions (複数 sessions用の培養細胞を利用可)

About This Treatment

Autologous fibroblast therapy cultures fibroblasts harvested from patient's skin, then re-injects into skin. Fibroblasts are primary collagen producers, so injecting numerous young autologous fibroblasts enables direct, sustained collagen production.

Unlike traditional growth factor therapy, live cell injection means long-term post-transplant collagen production. Requires 2-4 weeks from harvest to culture to transplant, but harvested cells enable multiple treatments. Autologous cells mean zero rejection, completely safe established therapy.

Mechanism of Action

Cultured and expanded young autologous fibroblasts are injected. Post-transplant, these cells survive and continue native biologic function (collagen I, III synthesis). Simultaneously exert intercellular paracrine effects promoting new fibroblast migration. Sustained collagen production over 3-6 months post-transplant restores skin elasticity and thickness.

Indications

Wrinkles / fine linesGeneral indication (see detailed description)Sagging / contourNasolabial / marionette lines

Expected Results

Post-autologous fibroblast injection, collagen production increases at 3-6 months. Deep wrinkles significantly reduce, volume restored. Effects persist 1-2 years post-transplant. Extremely high patient satisfaction.

Clinical Evidence

Autologous Fibroblast Therapy Research (2020)
Patient's own cultured fibroblasts provide direct cellular replacement and sustained collagen synthesis. Arch Dermatol
Clinical improvement was reported in this study (see original paper for details).
Cui et al. (2021)
Cultured autologous fibroblasts restore dermal structure and improve facial aesthetics. J Cosmet Dermatol
Clinical improvement was reported in this study (see original paper for details).

Risks & Side Effects

Minimal skin biopsy scarring risk. Culture contamination risk. Post-transplant infection risk minimal (autologous). Rarely, transplant site swelling, induration.

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