Revitalizing Supreme+ Peptide Cream

Multi-peptide formula boosting collagen production

Key Ingredients

パルミトイルトリペプチド-1（Matrixyl）

Signal peptide stimulating collagen I, III, IV synthesis. Activates fibroblasts to strengthen dermal structure.

モリンガエキス

Potent antioxidant and anti-glycation compound. Inhibits AGE formation, preventing collagen elasticity loss.

ヒアルロン酸 + スクワラン

Dual-layer hydration approach providing both water retention and emolliency.

How It Works

Palmitoyl tripeptide-1 is a TGF-β mimetic peptide activating fibroblast TGF-β receptors, upregulating ECM protein gene expression (type I/III collagen, fibronectin, hyaluronic acid). Moringa extract isothiocyanates inhibit the Maillard reaction forming AGEs, preventing collagen fiber cross-linking and stiffening. Result: restored dermal elasticity and thickness, reduced wrinkle depth.

How to Use

Apply pearl-sized amount after serum to face, neck, and décolleté, AM and PM. Safe for eye area. Layer extra on wrinkle-prone areas (eyes, nasolabial folds, forehead).

Expected Results

Improved firmness and elasticity at 2-4 weeks. Fine wrinkles less visible at 4-8 weeks. 3+ months shows improvement in deeper wrinkles (nasolabial folds, eye area).

Scientific Evidence

Lintner K, Peschard O (2000)

Biologically active peptides: from a laboratory bench curiosity to a functional skin care product. Int J Cosmet Sci

ペプチドの皮膚科学応用を初めて包括的にレビュー。パルミトイルペプチドのコラーゲン合成刺激効果を確認。

Robinson LR, Fitzgerald NC, Doughty DG, et al. (2005)

Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. Int J Cosmet Sci

パルミトイルペプチドの12週間外用で、光老化によるシワが有意に改善。プラセボ対照二重盲検試験で実証。

Gkogkolou P, Böhm M (2012)

Advanced glycation end products: key players in skin aging?. Dermato-Endocrinology

AGEsが皮膚老化の主要メカニズムであることを詳述。抗糖化成分によるコラーゲン保護の有効性を確認。

Precautions

Rare hypersensitivity to peptide ingredients reported. Patch test recommended on first use. Consider trying samples or travel size first given higher price point.

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■ Disclaimer

Information on this page is based on scientific literature and does not guarantee product results. Effects vary by individual. Discontinue use and consult a dermatologist if skin issues occur.